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Missing Poster has the lowest priority of all / the second lowest priority of all, with only Tainted Lost's Birthright effect being lower.
Resurrection items activate in a set order.None of the effects will occur during any Challenges.If The Lost is already unlocked, revives Isaac as The Lost if he dies anywhere, then disappears. Dying in a Sacrifice Room while holding it unlocks The Lost.If Isaac dies to a Sacrifice Room's spikes, a puzzle piece will appear on his last will.